FIGURE

Fig. 5

ID

ZDB-FIG-200610-5

Publication

Di Martile et al., 2020 - Inhibition of lysine acetyltransferases impairs tumor angiogenesis acting on both endothelial and tumor cells

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Fig. 5

a Representative images of immunofluorescence for DNA (blue), GFP (green), and acetylated α-tubulin (red) of A549 cells overexpressing α-tubulin WT-GFP (A549-GFP-Tub) or α-tubulin K40R-GFP (A549-GFP-Tub-K40R). Scale bar, 10 μm. b-e Quantification of migration rate of A549 cells (b) overexpressing α-tubulin WT-GFP, and (d) α-tubulin K40R-GFP treated with CPTH6 for 48 h and subjected to time-lapse videorecording using a 10X objective. The sheet migration rates of two different conditions (control and CPTH6-treated) were determined by plotting the binary area versus time. c,e The migration rates of A549 cells (c) overexpressing α-tubulin WT-GFP and (e) α-tubulin K40R-GFP in response to CPTH6 were determined as the percentage of wound closure. p values were calculated between control and treated cells. *p < 0.05

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ J. Exp. Clin. Cancer Res.