ZFIN ID: ZDB-FIG-200430-1
Park et al., 2020 - Zebrafish B cell acute lymphoblastic leukemia: new findings in an old model. Oncotarget   11:1292-1305 Full text @ Oncotarget
ADDITIONAL FIGURES
PHENOTYPE:
Fish:
Observed In:
Stage: Adult

Figure 1 B-ALL in <italic>hMYC</italic> zebrafish.

(A) Curves displaying B- and T-ALL incidence by 184 dpf, as determined by fluorescence microscopy. (B) Fluorescence microscopy images of fish with B-ALL (left), both B- and T-ALL (center), or T-ALL (right). Flow cytometry plots of ALL samples from these fish are shown beneath them. (C) B-ALL appearance in fish with rag2:hMYC and different transgenic markers: cd79a:GFP (left), cd79b:GFP (center), or lck:GFP (right). WT cd79a:GFP or cd79b:GFP fish without B-ALL are shown beneath for comparison. Images are representative of > 50 animals examined for each genotype.

Gene Expression Details No data available
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
cz2Tg; zdf14Tg standard conditions Adult whole organism Lymphoid neoplasms present, abnormal
fcc90Tg; zdf14Tg standard conditions Adult whole organism Lymphoid neoplasms present, abnormal
fcc97Tg; zdf14Tg standard conditions Adult whole organism Lymphoid neoplasms present, abnormal
Acknowledgments:
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Oncotarget