FIGURE

Fig. 4

ID

ZDB-FIG-200207-15

Publication

Mourabit et al., 2019 - New insights into organ-specific oxidative stress mechanisms using a novel biosensor zebrafish

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Fig. 4

Concentration-dependent tissue responses in Tg (3EpRE:hsp70:mCherry) zebrafish larvae exposed to cisplatin. Fish larvae were exposed to solvent control (Ai-v) and three concentrations of cisplatin (Bi-v; Ci-v; Di-v) from 2 to 4 dpf and subsequently imaged via epifluorescence and confocal microscopy. Confocal images of a lateral line neuromast labelled with SYTO24 and EpRE-mCherry expression and their colocalization, under control (Aii-v) and cisplatin exposed conditions (Bii-iv, Cii-iv, Dii-iv). Confocal images of a pronephric convoluted tubule under control (Av) and 100 μM cisplatin (Dv) Arrowheads = neuromast; arrow = pronephric convoluted tubule. For images A–D, fluorescence intensity is represented using a “Fire” lookup table with a 0–255 pixel intensity calibration bar. Nominal cisplatin culture medium concentrations displayed.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

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