FIGURE

Figure 2—figure supplement 1

ID

ZDB-FIG-191230-1582

Publication

Morishita et al., 2019 - A critical role of VMP1 in lipoprotein secretion

Other Figures

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Figure 2—figure supplement 1

Large lipid-containing structures are not observed in the brain and skeletal muscle of vmp1^-/- zebrafish or in the intestine of rb1cc1^-/- and atg5^-/- zebrafish.

(A) Oil red O and hematoxylin staining of 6-dpf vmp1^+/- and vmp1^-/- zebrafish. Data are representative of two independent experiments. Scale bars, 100 μm. (B) and (C) Transmission electron microscopy of the hindbrain (B) and skeletal muscle (C) from 6-dpf vmp1^+/- and vmp1^-/- zebrafish. Data are representative of two independent experiments. Scale bars, 1 μm. (D) and (E) Transmission electron microscopy of the intestine from 6-dpf rb1cc1^+/-, rb1cc1^-/- (D), atg5^+/- and atg5^-/- (E) zebrafish. L, lumen of the intestine. Data are representative of two independent experiments. Scale bars, 5 μm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	atg5^jt4/jt4 (RW) rb1cc1^jt1/jt1 (RW) vmp1^jt3/jt3 (RW) atg5^jt4/+ (RW) rb1cc1^jt1/+ (RW) vmp1^jt3/+ (RW)
Observed In:	hindbrain lipid intestine lipid skeletal muscle lipid
Stage:	Day 6

Phenotype Detail

Acknowledgments

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