FIGURE

Fig. 2

ID
ZDB-FIG-191014-12
Publication
Wang et al., 2019 - Inhibition of COX-2, mPGES-1 and CYP4A by isoliquiritigenin blocks the angiogenic Akt signaling in glioma through ceRNA effect of miR-194-5p and lncRNA NEAT1
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Fig. 2

20-HETE or PGE2 partly reverses the antiangiogenic activities of the screened molecules in the zebrafish embryo. a The zebrafish embryos in 96-well microplate were treated with the indicated concentrations of compounds [isoliquiritigenin (ISL), glabridin (GLA) and hesperetin (HSP), 10 μM] alone, the compounds (10 μM) plus 20-HETE or PGE2, and vehicle for 48 h. Selected images of angiogenesis in the zebrafish embryo in different groups as shown in (a); Average vessel length for each group (b). The values are presented as the mean ± SEM, n = 20. *P < 0.05; **P < 0.01 vs. control; #P < 0.05; ##P < 0.01 vs. ISL, GLA or HSP-treated groups

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data

Phenotype Detail
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ J. Exp. Clin. Cancer Res.