FIGURE

Fig. 3

ID
ZDB-FIG-190814-20
Publication
Pei et al., 2018 - Guided genetic screen to identify genes essential in the regeneration of hair cells and other tissues
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Fig. 3

Mutations specifically affecting hair cell regeneration. a A fluorescent image of a zebrafish embryo at 5 dpf stained with Yopro-1, showing the distribution of neuromast hair cells. Arrows point to the P1–P4 neuromasts that were used for hair cell counting. b A magnified image of neuromast hair cells in the P1 neuromast. cg Quantification of impaired hair cell regeneration caused by rnpc3la028632 retroviral insertional mutation (c), hspe1hg77 (6 bp CRISPR deletion) mutation (d), hspa13hg78 (12 bp CRISPR deletion) mutation (e), smn1fh299 (ENU missense Y262X) mutation (f), and gemin5hg80(1 bp CRISPR deletion) mutation (g). The graphs are obtained from analyzing and then genotyping ~45 embryos generated from a pairwise incross of heterozygotes. Graphs show the mean and s.e.m. The difference between the wild-types and homozygotes is significant for all mutations (p < 0.05)

 

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data
Fish:
Condition:
Observed In:
Stage: Day 5

Phenotype Detail
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ NPJ Regen Med