FIGURE

Figure 5

ID

ZDB-FIG-190723-2518

Publication

Amigo et al., 2018 - The Reprimo Gene Family: A Novel Gene Lineage in Gastric Cancer with Tumor Suppressive Properties

Other Figures

All Figure Page

Back to All Figure Page

Figure 5

Unanswered questions in RPRM gene family. RPRM is as a p53-induced protein which induces cell cycle arrest at the G2/M checkpoint [4], through an unknown mechanism. Recently, RPRM genes have been shown to be expressed during brain, gut and blood vessel development [2]. Additional functions for RPRM include its role as a potential tumor suppressor gene (TSG), and a biomarker—through the assessment of the methylation status of its promoter region—for non-invasive detection of gastric cancer and other tumors [48,62]. Much like RPRM, RPRML is also expressed during embryonic development [2], but its role in physiological processes has never been investigated.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Int. J. Mol. Sci.