FIGURE

FIGURE 1

ID

ZDB-FIG-190723-2029

Publication

de Pater et al., 2018 - Bloody Zebrafish: Novel Methods in Normal and Malignant Hematopoiesis

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FIGURE 1

(A) Overview of definitive hematopoietic sites in the developing embryo where HSPCs are born from hemogenic endothelial cells of the dorsal aorta (DA). HSPCs are amplified in the caudal hematopoietic tissue (CHT) and migrate to the kidney and thymus. (B) Endothelial-to-hematopoietic transition (EHT) event imaged in a Tg(fli:GFP) embryo between 32 and 40 hpf. (C) CHT region in Tg(flt:RFP)/Tg(CD41:GFP) embryo at 56 hpf indicating erythroid myeloid progenitors (EMP) in green and definitive HSPCs in yellow as they originate from the artery and retain RFP at this timepoint. (D) Sagittal section through an adult zebrafish where the head kidney is indicated with enlargement showing the hematopoietic cells in between the kidney tubules.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front Cell Dev Biol