FIGURE

Fig. 4

ID
ZDB-FIG-181022-5
Publication
Lawrence et al., 2018 - The mechanical impact of col11a2 loss on joints; col11a2 mutant zebrafish show changes to joint development and function, which leads to early-onset osteoarthritis.
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Fig. 4

Shape changes in col11a2 zebrafish mutants have a greater effect on jaw biomechanics than material property changes. (a,b) FE models of maximum (EMax) and minimum (EMin) principal strain during mouth opening in 7 dpf wt and col11a2−/− zebrafish. Red arrowheads, areas of high strain; black arrowheads, areas of low strain; black asterisks, jaw joint. (a) wt jaw shape with wt material properties and col11a2−/− shape with col11a2−/− material properties. (b) wt shape with col11a2−/− material properties and col11a2−/− shape with wt material properties. Ventral and lateral views shown for each condition.

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data

Phenotype Detail
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Phil. Trans. Roy. Soc. Lond., Series B