FIGURE
Fig. S6
- ID
- ZDB-FIG-181022-12
- Publication
- Lawrence et al., 2018 - The mechanical impact of col11a2 loss on joints; col11a2 mutant zebrafish show changes to joint development and function, which leads to early-onset osteoarthritis.
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Fig. S6
Shape changes in col11a2 zebrafish mutants have greater affect on jaw biomechanics than material property changes. A,B) Finite Element (FE) models of maximum (E. Max) and minimum (E. Min) principal strain during mouth closing in 7dpf wt and col11a2-/- zebrafish. Red arrowheads = areas of high strain, black asterisks = jaw joint. A) wt jaw shape with wt material properties and col11a2-/- shape with col11a2-/- material properties. B) wt shape with col11a2-/- material properties and col11a2--/- shape with wt material properties. Ventral and lateral views shown for each. |
Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
Phenotype Detail
Acknowledgments
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Full text @ Phil. Trans. Roy. Soc. Lond., Series B