Fig. 7
- ID
- ZDB-FIG-180420-58
- Publication
- Raghupathy et al., 2017 - Rpgrip1 is required for rod outer segment development and ciliary protein trafficking in zebrafish
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Impairment of visual function in rpgrip1 −/− zebrafish. (A) Representative ERG traces from wildtype and rpgrip1 −/− zebrafish at 7dpf. D-wave was absent in the mutant zebrafish. (B) b-wave amplitudes of rpgrip1 −/− zebrafish (n = 10) were significantly reduced when compared to wildtype siblings (n = 11). The result is shown as mean ± SD. SD: standard deviation. **p < 0.01. (C) Visual background adaption for wildtype (n = 10) and rpgrip1 −/− zebrafish (n = 10) at 7dpf responding to dark adaption and bright light stimulation. Representative images showing that melanin of wildtype zebrafish was aggregated into small granules after light adaption, while rpgrip1 −/− zebrafish displayed larger diffused melanin granules. |
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Observed In: | |
Stage: | Days 7-13 |