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Fig. 6

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ZDB-FIG-170426-12

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Li et al., 2009 - Medaka vasa is required for migration but not survival of primordial germ cells

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Fig. 6

Analyses of RNA expression profiles of wt1a, sdf1b and cxcr4b by whole mount in situ hybridization. Normal expression of wt1a, sdf1b and cxcr4b is seen in MOvas-injected embryos compared to MOvc-injected control embryos. By stage 22, wt1a is expressed in lateral plate mesoderm (lpm), sdf1b is high in the lpm and presomitic mesoderm (psm) and weak in the telencaphalon (tp), whereas cxcr4b is abundant in posterior lateral line placodes (pllp), olfactory placodes (op) and weak in the lateral somatic area where PGCs normally reside (dot line). By stage 34, similar expression patterns of the three genes are also seen in MOvas- and MOvc-injected embryos. gd, gonad; mn and pn, meso- and pronephros. Shown are representatives of 50 embryos in each experiment.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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Reprinted from Mechanisms of Development, 126(5-6), Li, M., Hong, N., Xu, H., Yi, M., Li, C., Gui, J., Hong, Y., Medaka vasa is required for migration but not survival of primordial germ cells, 366–381, Copyright (2009) with permission from Elsevier. Full text @ Mech. Dev.