FIGURE

Fig. S8

ID

ZDB-FIG-170110-37

Publication

Xiao et al., 2016 - Chromatin-remodelling factor Brg1 regulates myocardial proliferation and regeneration in zebrafish

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Fig. S8

Inhibition of brg1 impairs cardiac regeneration. (a-c) BrdU⁺/Mef2C⁺ proliferating cardiomyocyte were comparable between wt sibling hearts (a) and dn-xBrg1 transgenic hearts (b) at 14 dpa without heat shock treatment [(-) HS]. (c) Percentages of BrdU⁺/Mef2C⁺ cardiomyocytes in the injured area. (d-f) PCNA⁺/ Mef2C⁺ proliferating cardiomyocytes (arrowheads) decreased in dn-xBrg1 tg hearts (e) compared with wt sibling hearts (d) at 14 dpa with heat shock treatment. (f) Quantification of cardiomyocyte proliferation assessed by PCNA⁺/ Mef2C⁺ staining Scale bars, 100 μm. Data presented are mean ± s.e.m.; paired Student’s t-test, sample numbers are listed under each group, ** p < 0.01.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Nat. Commun.