ZFIN ID: ZDB-FIG-161222-32
Alvarado et al., 2016 - Wdr68 Mediates Dorsal and Ventral Patterning Events for Craniofacial Development. PLoS One   11:e0166984 Full text @ PLoS One
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Genes:
Fish:
Condition:
Anatomical Terms:
Stage: Prim-25
PHENOTYPE:
Fish:
Condition:
Observed In:
Stage: Prim-25

Fig. 3

Wdr68 restricts expression of jag1b, hey1, and grem2 from ventral territory.

ISH analysis on embryos raised at 32°C. A) normal expression of jag1b in dorsal territory at the prim-25 stage, B) expansion of jag1b into ventral territory in wdr68hi3812/hi3812 mutants, C) normal expression of hey1 in dorsal territory at the prim-25 stage, D) expansion of hey1 into ventral territory in wdr68hi3812/hi3812 mutants, E) normal expression of grem2 in dorsal territory at the prim-25 stage, F) expansion of grem2 into ventral territory in wdr68hi3812/hi3812 mutants.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
grem2b WT heat exposure Prim-25 pharyngeal arch 1 dorsal region ISH
dcaf7hi3812Tg/hi3812Tg heat exposure Prim-25 pharyngeal arch 1 dorsal region ISH
Prim-25 pharyngeal arch 1 ventral region ISH
hey1 WT heat exposure Prim-25 pharyngeal arch 1 dorsal region ISH
dcaf7hi3812Tg/hi3812Tg heat exposure Prim-25 pharyngeal arch 1 dorsal region ISH
Prim-25 pharyngeal arch 1 ventral region ISH
jag1b WT heat exposure Prim-25 pharyngeal arch 1 dorsal region ISH
dcaf7hi3812Tg/hi3812Tg heat exposure Prim-25 pharyngeal arch 1 dorsal region ISH
Prim-25 pharyngeal arch 1 ventral region ISH
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
dcaf7hi3812Tg/hi3812Tg heat exposure Prim-25 pharyngeal arch 1 ventral region grem2b expression mislocalised, abnormal
Prim-25 pharyngeal arch 1 ventral region hey1 expression mislocalised, abnormal
Prim-25 pharyngeal arch 1 ventral region jag1b expression mislocalised, abnormal
Acknowledgments:
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