ZFIN ID: ZDB-FIG-161201-26
Monroe et al., 2016 - Hearing sensitivity differs between zebrafish lines used in auditory research. Hearing Research   341:220-231 Full text @ Hear. Res.
ADDITIONAL FIGURES
PHENOTYPE:
Fish:
Observed In:
Stage: Adult

Fig. 6

Hair bundle density in the lagena. (A) Lagena schematic showing the three sampling locations, with an example of location 2 shown in the confocal image. All boxes are 50 × 50 μm and are drawn to scale. (B) For *AB and transgenic lines created on the *AB background, bundle density is significantly different between genotypes and sampling regions (2-way ANOVA, F5,160 = 8.91, p < 0.001; and F2,160 = 43.02, p < 0.001, respectively). In sampling region 3, bundle density is significantly higher in Bcl2 fish than in *AB fish (Bonferroni-corrected posthoc, ***p < 0.001). (C) There is a significant difference in lagenar bundle density between wildtype lines (2-way ANOVA, F2,68 = 9.08, p < 0.001 for genotype main effect), with WIK fish having higher density in region 3 than AB fish (*p < 0.05). (D) There is no difference in bundle density between ET4 and TL fish (2-way ANOVA, F1,24 = 0.40, p = 0.53 for genotype main effect). Data are presented as mean ± S.E. N = 8–17 fish per genotype.

Gene Expression Details No data available
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
w124Tg (AB) standard conditions Adult lagena actin filament bundle of stereocilium condensed, abnormal
Acknowledgments:
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Reprinted from Hearing Research, 341, Monroe, J.D., Manning, D.P., Uribe, P.M., Bhandiwad, A., Sisneros, J.A., Smith, M.E., Coffin, A.B., Hearing sensitivity differs between zebrafish lines used in auditory research, 220-231, Copyright (2016) with permission from Elsevier. Full text @ Hear. Res.