FIGURE

Fig. 1

ID

ZDB-FIG-160715-14

Publication

Wei et al., 2016 - RNA polymerase III component Rpc9 regulates hematopoietic stem and progenitor cell maintenance in zebrafish

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Fig. 1

T cells are absent in mutant line 116 embryos. (A,B) WISH showing that early T cell markers (rag1, rag2 and bcl11b), HSPC markers (cmyb and ikaros) and T cell markers (ccr9a, ccr9b, tcrb2 and tcrd) are absent in the thymus of mutant line 116 at 5dpf. By contrast, thymus epithelial cell marker foxn1 was normal in the thymus of 116 mutants at 5dpf. Red arrowheads indicate the thymus. Numbers at bottom right indicate the number of embryos with similar staining pattern among all embryos examined.

Expression Data

Genes:	bcl11ba ccr9a ccr9b foxn1 ikzf1 linc-tcrb myb rag1 rag2 trdc (all 10)
Fish:	AB crcp^hkz8/hkz8
Anatomical Terms:	thymic epithelium thymus hematopoietic multipotent progenitor cell thymus T cell
Stage:	Day 5

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	crcp^hkz8/hkz8
Observed In:	thymus thymus hematopoietic multipotent progenitor cell thymus T cell
Stage:	Day 5

Phenotype Detail

Acknowledgments

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