FIGURE

Fig. 5

ID

ZDB-FIG-151123-2

Publication

Liang et al., 2015 - Kaempferol Identified by Zebrafish Assay and Fine Fractionations Strategy from Dysosma versipellis Inhibits Angiogenesis through VEGF and FGF Pathways

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Fig. 5

Kaempferol inhibits VEGF-induced migration and tube formation of HUVECs

(A) upper row, kaempferol inhibited VEGF-induced HUVECs migration in wound healing assay. HUVECs were allowed to grow into full confluence in 24–well plates. Cells were wounded with a pipette and treated with or without 40 ng/mL VEGF and different concentrations of kaempferol in ECM supplemented with 0.5% (v/v) FBS. Compared to control group, 40 µM kaempferol blocked induction by VEGF. Bottom row, kaempferol inhibited VEGF-induced HUVEC tube formation. (B,C) quantification of the results in (A). Image J was applied for statistical branching point numbers and the distance of remained gap. Scale bar, 100 µm. *P < 0.05 versus control group.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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