FIGURE

Fig. 4

ID

ZDB-FIG-150401-17

Publication

Xu et al., 2014 - Maternal Vsx1 plays an essential role in regulating prechordal mesendoderm and forebrain formation in zebrafish

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Fig. 4

Maternal Vsx1 knockdown specifically inhibits forebrain formation. (A-F′) Expression patterns of six3b, eng2a and krox20 in uninjected wild-type and vsx1 tbMO injected embryos at 8-10 somite embryos. (G-H′) Comparison of relative expression levels and spatial patterns of forebrain marker rx3, mid-hindbrain boundary marker pax2a and hindbrain marker hoxb1b at bud stage. Brackets in G and H indicate the distance between forebrain region and mid-hindbrain boundary. Asterisks indicate the anterior end of forebrain. Black arrowheads indicate the location of mid-hindbrain boundary and gray arrowheads indicate the location of hindbrain. (A-H) Dorsal views with animal to the top. (A′-H′) Lateral views with animal to the top. The injected reagents are indicated at the left of each column. Riboprobes are indicated at the top of each group of figures.

Expression Data

Genes:	egr2b en2a hoxb1b pax2a rx3 six3b
Fish:	WT WT + MO2-vsx1
Knockdown Reagent:	MO2-vsx1
Anatomical Terms:	forebrain forebrain neural plate hindbrain hindbrain neural plate midbrain midbrain hindbrain boundary neural plate
Stage Range:	Bud to 10-13 somites

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT + MO2-vsx1
Knockdown Reagent:	MO2-vsx1
Observed In:	forebrain development
Stage Range:	Bud to 10-13 somites

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 394(2), Xu, X., He, Y., Sun, L., Ma, S., Luo, C., Maternal Vsx1 plays an essential role in regulating prechordal mesendoderm and forebrain formation in zebrafish, 264-76, Copyright (2014) with permission from Elsevier. Full text @ Dev. Biol.