FIGURE
Fig. 2
- ID
- ZDB-FIG-150129-10
- Publication
- Zhao et al., 2014 - Leptin and IL-6 Family Cytokines Synergize to Stimulate Müller Glia Reprogramming and Retina Regeneration
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Fig. 2
The Jak/Stat3 Signaling Pathway Is Necessary for Retina Regeneration (A) BrdU immunofluorescence shows that the Jak inhibitors P6 and JSI-124 suppress progenitor formation at 4 dpi. The asterisk marks the injury site (needle poke) and arrows point to MG-derived progenitors. (B) Quantification of BrdU+ progenitors in (A). p < 0.001, n = 4. (C) qPCR shows that the Jak inhibitors P6 and JSI-124 inhibit reprogramming gene induction at 2 dpi; p < 0.01, p < 0.001; n = 4, 4, and 5 for DMSO, P6, and JSI-124, respectively. Error bars, SD. Scale bars, 20 µm (A). See also Figure S3. |
Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
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| Conditions: | |
| Observed In: | |
| Stage: | Adult |
Phenotype Detail
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