ZFIN Figure: Boczonadi et al., 2014, text only

ZFIN ID: ZDB-FIG-140930-9

ZFIN ID: ZDB-FIG-140930-9

Boczonadi et al., 2014 - EXOSC8 mutations alter mRNA metabolism and cause hypomyelination with spinal muscular atrophy and cerebellar hypoplasia. Nature communications 5:4287 Full text @ Nat. Commun.

ADDITIONAL FIGURES

PHENOTYPE:

Fish:	rw0Tg + MO1-exosc8 rw0Tg + MO2-exosc8
Knockdown Reagents:	MO1-exosc8 MO2-exosc8
Observed In:	brain development eye pericardium post-vent region sensory perception of touch swimming whole organism
Stage:	Long-pec

Unillustrated author statements

Gene Expression Details No data available

Antibody Labeling Details No data available

Phenotype Details

Fish	Conditions	Stage	Phenotype
rw0Tg + MO1-exosc8	standard conditions	Long-pec	sensory perception of touch disrupted, abnormal
		Long-pec	swimming disrupted, abnormal
rw0Tg + MO2-exosc8	standard conditions	Long-pec	brain development disrupted, abnormal
		Long-pec	eye decreased size, abnormal
		Long-pec	eye shape, abnormal
		Long-pec	pericardium edematous, abnormal
		Long-pec	post-vent region decreased length, abnormal
		Long-pec	sensory perception of touch disrupted, abnormal
		Long-pec	swimming disrupted, abnormal
		Long-pec	whole organism malformed, abnormal

Acknowledgments:
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Nat. Commun.