FIGURE

Fig. 4

ID

ZDB-FIG-140908-4

Publication

Benato et al., 2014 - A living biosensor model to dynamically trace glucocorticoid transcriptional activity during development and adult life in zebrafish

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Fig. 4

Transgenic line responses to different steroid treatments. (A) Light microscopy dorsal view and (B) fluorescence microscopy images of 3-dpf transgenic zebrafish treated for 48 h with the indicated compounds. In (A) responses were visualized by WMISH of egfp mRNA. Cortisol, dexamethasone, prednisolone, progesterone and corticosterone treatments increased reporter activity compared to control, while no changes were detectable with 11β-deoxycorticosterone (DOC), aldosterone, 11-ketotestosterone and 17β-estradiol (E2). Scale bar: 200 µM.

Expression Data

Gene:	EGFP
Fish:	ia20Tg
Condition:	chemical treatment: pharmaceutical
Anatomical Term:	head
Stage:	Protruding-mouth

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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Reprinted from Molecular and Cellular Endocrinology, 392(1-2), Benato, F., Colletti, E., Skobo, T., Moro, E., Colombo, L., Argenton, F., Dalla Valle, L., A living biosensor model to dynamically trace glucocorticoid transcriptional activity during development and adult life in zebrafish, 60-72, Copyright (2014) with permission from Elsevier. Full text @ Mol. Cell. Endocrinol.