FIGURE

Fig. 4

ID

ZDB-FIG-140428-27

Publication

Graciarena et al., 2014 - Dynamics of axonal regeneration in adult and aging zebrafish reveal the promoting effect of a first lesion

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Fig. 4

Involvement of Schwann cells in axonal regeneration. (A) Three days after nerve cut in 1-mpf fishes, the axons have fully degenerated (double-headed arrow), but Schwann cells (arrowheads) are not noticeably affected posterior to the leading growth cones (arrows). (B) During regeneration, the leading growth cone (arrows) and neurite (double arrow) are closely apposed to Schwann cells (arrowheads). (C) 2 d after nerve ablation, Schwann cells are still absent from the exposed region (double-headed arrow), yet the growth cones of regenerating neurites (arrowheads) have crossed the glial gap. Regenerating neurites are notably defasciculated over the ablated region (arrows). (Scale bars, 50 μm for A and B; 100 μm for C.)

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Proc. Natl. Acad. Sci. USA