FIGURE

Fig. S8

ID

ZDB-FIG-131029-47

Publication

Novikov et al., 2013 - Tmem88a mediates GATA-dependent specification of cardiomyocyte progenitors by restricting WNT signaling

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Fig. S8

Tmem88a depletion selectively affects lateral mesoderm derivatives including erythromyeloid progenitors. Flatmount preparations of representative 8- to 10-somite stage control (Ctrl) and tmem88a (88a) morphant embryos processed by WISH for (A,B) ntl⁺ axial mesoderm, (C,D) myod⁺ paraxial mesoderm, (E,F) pax2a⁺ intermediate mesoderm and (G,H) scl⁺ hematovascular domains in the context of ntl. (I,J) gata1⁺ hematopoietic progenitors. n>20 embryos per condition. (K) Relative expression levels by qPCR for various hematopoietic and vascular markers. **P<0.01.

Expression Data

Genes:	gata1a myod1 pax2a tal1 tbxta
Fish:	WT WT + MO3-tmem88a + MO4-tmem88a
Knockdown Reagents:	MO3-tmem88a MO4-tmem88a
Anatomical Terms:	axial mesoderm intermediate mesoderm paraxial mesoderm posterior lateral plate mesoderm
Stage:	5-9 somites

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT + MO3-tmem88a + MO4-tmem88a
Knockdown Reagents:	MO3-tmem88a MO4-tmem88a
Observed In:	posterior lateral plate mesoderm
Stage:	5-9 somites

Phenotype Detail

Acknowledgments

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