FIGURE

Fig. 7

ID

ZDB-FIG-121212-41

Publication

Gyda et al., 2012 - The tumor suppressor gene retinoblastoma-1 is required for retinotectal development and visual function in zebrafish

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Fig. 7

Intraretinal and midline RGC axon pathfinding errors in rb1^te226a mutants.

(A-C) Dorsal, intraretinal views of DiO (green) labeled anterior and DiI (red) labeled posterior RGCs. (D-F) Lateral, intraretinal views of DiO/DiI labeled RGCs. (G-L) Dorsal views of retinotectal projection labeled by whole retina fills with DiI/DiO. Eyes removed in H-I, K-L. Dashed circles indicate retinal exit point. Arrows mark misprojecting axons. Asterisk shows optic nerve hypoplasia. Arrowheads mark ipsilateral tectal innervation. Abbreviations: (a) anterior, (p) posterior, (e) eye. Scale bar = 50 μm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	rb1^{te226a/te226a}
Observed In:	innervation retinal ganglion cell axon guidance
Stage:	Day 5

Phenotype Detail

Acknowledgments

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