FIGURE

Fig. 8

ID
ZDB-FIG-120829-1
Publication
Takada et al., 2011 - swap70 Promotes neural precursor cell cycle exit and oligodendrocyte formation
Other Figures
All Figure Page
Back to All Figure Page
Fig. 8

Swap70 loss-of-function does not affect OPC morphology and differentiation. Images of migrating OPCs (A, B) and wrapping oligodendrocytes (C, D) in living 3 dpf larvae visualized using a Tg(nkx2.2a:mEGFP) transgenic reporter. Membrane processes of OPCs and myelinating oligodendrocytes appear normal in MOswap70-sp-injected larvae. (E, F) plp1a mRNA expression at 3 dpf. (G, H) mbp mRNA expression at 3 dpf. Both plp1a and mbp appear to be expressed at normal levels in MOswap70-sp-injected larvae, although the number of cells expressing these genes in MO-injected larvae is fewer than in wild type.

Expression Data
Genes:
Fish:
Knockdown Reagent:
Anatomical Term:
Stage: Protruding-mouth

Expression Detail
Antibody Labeling
Phenotype Data
Fish:
Knockdown Reagent:
Observed In:
Stage: Protruding-mouth

Phenotype Detail
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image.

Reprinted from Molecular and cellular neurosciences, 48(3), Takada, N., and Appel, B., swap70 Promotes neural precursor cell cycle exit and oligodendrocyte formation, 225-35, Copyright (2011) with permission from Elsevier. Full text @ Mol. Cell Neurosci.