FIGURE

Fig. 2

ID

ZDB-FIG-120517-14

Publication

Shao et al., 2012 - GSK-3 Activity Is Critical for the Orientation of the Cortical Microtubules and the Dorsoventral Axis Determination in Zebrafish Embryos

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Fig. 2

0-mpf lithium treatment activates Wnt/β-catenin signaling at mid-blastula stage and expands the organizer region.

(A and B) Confocal immunofluoresence image of of β-catenin in a 0-mpf NaCl treated embryo (A) and a 0-mpf lithium treated embryo (B) To ensure that the entire marginal zone is investigated, each embryo was scanned for two focal planes near the marginal zone of two hemispheres. The embryos were at sphere stage. Nuclear β-catenin was marked with white asterisks. (C–E) Expression pattern of organizer gene gsc in untreated (C), 0-mpf lithium treated (D), and 2-cell-stage lithium treated (E) embryos. All the embryos were animal pole view, dorsal up if it can be distinguished.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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