FIGURE

Fig. 6

ID
ZDB-FIG-111214-29
Publication
Teng et al., 2011 - Loss of Zebrafish lgi1b Leads to Hydrocephalus and Sensitization to Pentylenetetrazol Induced Seizure-Like Behavior
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Fig. 6

Analysis of c-fos expression as a marker for seizure-like behavior. Increased expression of c-fos in lgi1a (MO-E3), but not lgi1b (MO-E2), morphants compared with corresponding mismatch (mis) MO treatment. RNA and protein extracts from 3 dpf embryos injected with 3 ng of the indicated morpholinos or wildtype were used for semi-qRT-PCR (A) and western blot assays (B), respectively. When lgi1 morphants (MO-E2) were treated with PTZ, an increase in c-fos expression was observed. No increase in c-fos was seen when mismatch morphants (MO-E3mis) were treated with PTZ.

Expression Data
Gene:
Fish:
Knockdown Reagents:
Anatomical Term:
Stage: Protruding-mouth

Expression Detail
Antibody Labeling
Phenotype Data
Fish:
Knockdown Reagent:
Observed In:
Stage: Protruding-mouth

Phenotype Detail
Acknowledgments
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