FIGURE
Fig. S4
- ID
- ZDB-FIG-110920-62
- Publication
- Bohnsack et al., 2011 - Phenothiourea Sensitizes Zebrafish Cranial Neural Crest and Extraocular Muscle Development to Changes in Retinoic Acid and IGF Signaling
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Fig. S4
T3 and T4 are required after 22 hpf for rescue of PTU. 96 hpf roy Tg(α-actin::EGFP) were treated with 100 nM T3 and 100 nM T4 from 6 to 22 hpf in the absence (A, B) or presence of 0.003% (C, D) or 0.03% (E, F) PTU from 6 to 96 hpf. Exposure to exogenous T3 and T4 only between 6 and 22 hpf in the absence of PTU (A, B) or in the presence of 0.003% PTU (C, D) did not cause frontal bossing or displacement of jaw cartilage as was seen with exposure to T3 and T4 from 6 to 96 hpf (Figure 7A-D). Furthermore, exogenous T3 and T4 from 6 to 22 hpf did not rescue the craniofacial defects induced by 0.03% PTU (E, F). |
Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
Phenotype Detail
Acknowledgments
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