FIGURE

Fig. 4

ID

ZDB-FIG-110622-50

Publication

Anastasaki et al., 2011 - Dhx34 and Nbas function in the NMD pathway and are required for embryonic development in zebrafish

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Fig. 4

Nbas is essential for zebrafish embryonic development. (A) Injections with translation block and splice site MOs against zebrafish nbas reproduced the developmental phenotype observed in Upf1 and Dhx34 morphants. (B) Co-injection of Nbas translation block MO and human full length NAG/Nbas mRNA rescued the morphant phenotype in the majority of the embryos at 24 hpf. Expression of the mRNA alone had no effect on embryonic development. The numbers beside each panel represent the percentage of embryos showing each phenotype and in brackets is the total number of the analysed embryos.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT + MO1-nbas WT + MO2-nbas
Knockdown Reagents:	MO1-nbas MO2-nbas
Observed In:	brain gastrulation somite
Stage:	Prim-5

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Nucleic Acids Res.