FIGURE

Fig. S1

ID

ZDB-FIG-101122-38

Publication

Soza-Ried et al., 2010 - Essential role of c-myb in definitive hematopoiesis is evolutionarily conserved

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Fig. S1

Phenotypic abnormalities in c-myb mutants. (A) Incomplete ossification in mutant fish (Lower; merged from three pictures) at 9 wk of age as revealed by alcian blue (cartilage) and alizarin red (red) staining. Note the stunted appearance and reduced bone structures. The photograph of the wild-type fish is a composite of two pictures. (Scale bar: 1 mm.) (B) Slightly reduced hemoglobin levels in mutant fish at 2 d postfertilization (dpf) as revealed by whole-mount o-dianisidine staining (orange color). Photographs are composites of three pictures. (C) Reduced hemoglobin levels in mutant fish at 9 dpf as revealed by whole-mount o-dianisidine staining. Photographs are composites of two pictures. (D) Lack of hemoglobin staining in the head kidney of mutants at 7 wk of age revealed by o-dianisidine staining on tissue sections. (Scale bar: 100 μm.)

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	myb^{t25127/t25127}
Observed In:	head kidney hematopoietic multipotent progenitor cell hemoglobin complex ossification involved in bone maturation whole organism hemoglobin complex
Stage Range:	Long-pec to Days 45-89

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Proc. Natl. Acad. Sci. USA