FIGURE

Fig. 2

ID

ZDB-FIG-091130-1

Publication

Hippe et al., 2009 - The interaction of nucleoside diphosphate kinase B with Gbetagamma dimers controls heterotrimeric G protein function

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Fig. 2

Cardiac dysfunction in NDPK B-depleted zebrafish embryos. Cardiac phenotype of wild-type (WT) (A) and NDPK B knockdown (B) embryos at 72 hpf. Fractional shortening (FS) of the atrial and ventricular chamber of WT (C) and NDPK B morphants (D) at 48 and 72 hpf. Data are means ± SEM, n = 11–21. Histology sections of a WT (E) and NDPK B knockdown (F) heart region stained with hematoxylin/eosin. A, atrium, V, ventricle, en, endocardial, my, myocardial layer. (G–J) Whole-mount immunofluorescence following staining with specific antibodies against atrial myosin heavy chain [S46, (G) and (I)] and entire heart tube myosin heavy chain [MF20, (H and J)] showing unaltered expression of structure proteins.

Expression Data

Gene:	myh6
Antibodies:	Ab-MF20 Ab-S46
Fish:	WT WT + MO2-nme2b.1
Knockdown Reagent:	MO2-nme2b.1
Anatomical Terms:	atrium cardiac ventricle
Stage:	Protruding-mouth

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT + MO2-nme2b.1
Knockdown Reagent:	MO2-nme2b.1
Observed In:	eye heart heart contraction pericardium
Stage Range:	Long-pec to Protruding-mouth

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Proc. Natl. Acad. Sci. USA