FIGURE

Fig. 1

ID
ZDB-FIG-090904-24
Publication
Mei et al., 2009 - hnRNP I is required to generate the Ca2+ signal that causes egg activation in zebrafish
Other Figures
All Figure Page
Back to All Figure Page
Fig. 1

brom bones mutants display impaired egg activation and dorsoventral patterning defects. (A) Wild-type (wt) 4-cell-stage zebrafish embryo at 60 mpa, with a fully elevated chorion (arrowheads). (B) Failed chorion elevation (arrows) and cytoplasmic segregation in brom bones mutant (brb) eggs at 60 mpa. Mutants have small blastodiscs (*) and slightly opaque yolk. (C) A wild-type embryo at oblong stage (a midblastula stage). (D) Moderately affected mutant embryos exhibit incomplete cellularization (arrow) and display large cytoplasmic inclusions in the yolk (arrowheads) at oblong stage. (E,F) Small cytoplasmic inclusions (arrowheads) are visible in the yolk of mildly affected mutant embryos (F) at gastrula stages, but not in wild-type embryos (E). (G) Wild-type embryo at 1 dpf. (H) Radially ventralized brom bones mutant embryo and (I-K) brom bones mutant embryos with decreasing strength of ventralization at 1 dpf. G-K are dissecting microscope images; rostral is towards the top and dorsal is to the right.

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data
Fish:
Observed In:
Stage Range: 1-cell to Prim-5

Phenotype Detail
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Development