FIGURE

Fig. 5

ID
ZDB-FIG-090127-24
Publication
Targoff et al., 2008 - Nkx genes regulate heart tube extension and exert differential effects on ventricular and atrial cell number
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Fig. 5

nkx genes play a critical role in early steps of heart tube extension. In situ hybridization depicts expression of cmlc2 (A,B), vmhc (C,D), and amhc (E,F) in wild-type (A,C,E) and nkx-deficient (B,D,F) embryos. Embryos viewed dorsally, anterior to the top, at 26 hpf. (A,B) nkx-deficient embryos exhibit prominent defects in heart tube extension, including a splayed and disorganized inflow region and an unusually compact outflow region. (C,D) In nkx-deficient embryos, the ventricular portion of the heart tube is abnormally short and wide. (E,F) In nkx-deficient embryos, the atrial portion of the heart tube is broad and sprawling.

Expression Data
Genes:
Fish:
Knockdown Reagents:
Anatomical Terms:
Stage: Prim-5

Expression Detail
Antibody Labeling
Phenotype Data
Fish:
Knockdown Reagents:
Observed In:
Stage: Prim-5

Phenotype Detail
Acknowledgments
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Reprinted from Developmental Biology, 322(2), Targoff, K.L., Schell, T., and Yelon, D., Nkx genes regulate heart tube extension and exert differential effects on ventricular and atrial cell number, 314-321, Copyright (2008) with permission from Elsevier. Full text @ Dev. Biol.