FIGURE

Fig. 2

ID

ZDB-FIG-081103-27

Publication

Thomas et al., 2008 - Hedgehog signaling plays a cell-autonomous role in maximizing cardiac developmental potential

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Fig. 2

Hedgehog signaling promotes the initial establishment of cardiomyocytes. (A-L) In situ hybridization detects expression of myocardial markers. Dorsal views, anterior towards the top. Scale bars: 100 μm (bar in D applies to D-I). MZsmo mutant and CyA-treated embryos exhibit reduced expression of (A-C) nkx2.5 at the seven-somite stage, (D-F) cmlc2 at the 18-somite stage, (G-I) vmhc at the 18-somite stage and (J-L) amhc at the 22-somite stage.

Expression Data

Genes:	myh6 myh7 myl7 nkx2.5
Fish:	WT smo^b577/b577
Condition:	chemical treatment: Cyclopamine
Anatomical Terms:	heart primordium heart rudiment
Stage Range:	5-9 somites to 20-25 somites

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT smo^b577/b577
Condition:	chemical treatment: Cyclopamine
Observed In:	heart primordium cardiac muscle myoblast heart primordium mesodermal cell
Stage Range:	5-9 somites to 20-25 somites

Phenotype Detail

Acknowledgments

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