FIGURE

Fig. S1

ID

ZDB-FIG-080722-2

Publication

Liedtke et al., 2008 - Midkine-b regulates cell specification at the neural plate border in zebrafish

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Fig. S1

Effect of DEAB and SU5402 treatment on neural plate size. Incubation of embryos in 10 μM DEAB from shield stage until 8.5 hpf results in reduction of mdkb expression (A,B; marked by arrows), while expression of tfap2 in non-neural ectoderm and neural plate size is not affected (E,F). Incubation of embryos with SU5402 results in a reduction of both, mdkb expression (C,D) and neural plate size as indicated by an expanded tfap2 expression domain (G,H). erm expression is reduced in SU5402 treated embryos (I, J, arrowhead), as described in the literature (Raible and Brand, 2001). (K,L) Phenotypes of live embryos at 24hpf treated with 50μM SU5402, note severe necrosis.

Expression Data

Genes:	etv5b mdkb tfap2a
Fish:	AB
Conditions:	chemical treatment: 4-(diethylamino)benzaldehyde chemical treatment: SU5402
Anatomical Terms:	neural plate non neural ectoderm unspecified
Stage Range:	75%-epiboly to 90%-epiboly

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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