FIGURE

Fig. 7

ID

ZDB-FIG-070307-8

Publication

Schafer et al., 2007 - Discontinuous organization and specification of the lateral floor plate in zebrafish

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Fig. 7

Knock-down of nkx2.2a interferes with LFP formation. (A, B) nkx2.2a morpholino injected embryos show reduction of nkx2.2b expression to single cells (B; for details, see text). (C–F) The LFP marker foxa2 is almost completely repressed in the LFP after nkx2.2a morpholino knock-down (D), while expression of tal2 in p3 neuronal progenitor cells is not affected (F). All pictures are dorsal views with anterior to the left. Scale bar in panel F is 20 μM.

Expression Data

Genes:	foxa2 nkx2.2b tal2
Fish:	WT WT + MO1-nkx2.2a
Knockdown Reagent:	MO1-nkx2.2a
Anatomical Terms:	lateral floor plate medial floor plate
Stage:	14-19 somites

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT + MO1-nkx2.2a
Knockdown Reagent:	MO1-nkx2.2a
Observed In:	floor plate formation lateral floor plate
Stage:	14-19 somites

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 301(1), Schafer, M., Kinzel, D., and Winkler, C., Discontinuous organization and specification of the lateral floor plate in zebrafish, 117-129, Copyright (2007) with permission from Elsevier. Full text @ Dev. Biol.