CRISPR

CRISPR4-foxc1b

ID
ZDB-CRISPR-200102-3
Name
CRISPR4-foxc1b
Previous Names
None
Target
Sequence
5' - CGACCGGTGGTGGATATACC - 3'
Disclaimer
Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.
Note
None
Genome Resources
None
Target Location
Constructs
No data available
Genomic Features
Genomic Feature Affected Genomic Regions
ua1018 foxc1b
Expression
Gene expression in Wild Types + CRISPR4-foxc1b
No data available
Phenotype
Phenotype resulting from CRISPR4-foxc1b
No data available
Phenotype of all Fish created by or utilizing CRISPR4-foxc1b
Phenotype Fish Conditions Figures
heart myl7 expression spatial pattern, abnormal foxc1bua1018/ua1018 (AB) standard conditions Figure 3 with image from Chrystal et al., 2021
determination of heart left/right asymmetry disrupted, abnormal foxc1bua1018/ua1018 (AB) standard conditions Figure 3 with image from Chrystal et al., 2021
whole organism col11a2 expression increased amount, abnormal foxc1bua1018/ua1018 (AB) standard conditions Figure 7 with image from Hawkey-Noble et al., 2022
neural crest pdgfra expression decreased amount, abnormal foxc1bua1018/ua1018 + MO2-foxc1a (AB) standard conditions Fig. S2 with image from Umali et al., 2019
solid lens vesicle pdgfra expression decreased amount, abnormal foxc1bua1018/ua1018 + MO2-foxc1a (AB) standard conditions Fig. S2 with image from Umali et al., 2019
retinal ganglion cell layer has fewer parts of type retinal ganglion cell, abnormal foxc1bua1018/ua1018 + MO2-foxc1a (AB) standard conditions Fig. 2 with image from Umali et al., 2019
retinal ganglion cell layer pou4f2 expression decreased amount, abnormal foxc1bua1018/ua1018 + MO2-foxc1a (AB) standard conditions Fig. 4 with image from Umali et al., 2019
retina atoh7 expression absent, abnormal foxc1bua1018/ua1018 + MO2-foxc1a (AB) standard conditions Fig. 4 with image from Umali et al., 2019
cranial nerve II decreased diameter, abnormal foxc1bua1018/ua1018 + MO2-foxc1a (AB) standard conditions Fig. 3 with image from Umali et al., 2019
retina atoh7 expression decreased amount, abnormal foxc1bua1018/ua1018 + MO2-foxc1a (AB) standard conditions Fig. 4 with image from Umali et al., 2019
pharyngeal arch pdgfra expression decreased amount, abnormal foxc1bua1018/ua1018 + MO2-foxc1a (AB) standard conditions Fig. S2 with image from Umali et al., 2019
head fgf19 expression decreased amount, abnormal foxc1bua1018/ua1018 + MO2-foxc1a (AB) standard conditions Fig. 5 with image from Umali et al., 2019
retinal ganglion cell neuron differentiation decreased occurrence, abnormal foxc1bua1018/ua1018 + MO2-foxc1a (AB) standard conditions Fig. 4 with image from Umali et al., 2019
heart edematous, abnormal foxc1aua1017/ua1017; foxc1bua1018/+ standard conditions Fig. S11 with image from Whitesell et al., 2019
ventral aorta vascular associated smooth muscle cell decreased amount, abnormal foxc1aua1017/ua1017; foxc1bua1018/+; ca7Tg/+; ci5Tg/+ standard conditions Fig. 8 with image from Whitesell et al., 2019
aortic arch myl9a expression decreased amount, abnormal foxc1aua1017/ua1017; foxc1bua1018/ua1018 standard conditions Fig. 8 with image from Whitesell et al., 2019
heart edematous, abnormal foxc1aua1017/ua1017; foxc1bua1018/ua1018 standard conditions Fig. S11 with image from Whitesell et al., 2019
vascular associated smooth muscle cell foxc1b expression decreased amount, abnormal foxc1aua1017/ua1017; foxc1bua1018/ua1018 standard conditions Fig. 8 with image from Whitesell et al., 2019
vascular associated smooth muscle cell foxc1a expression decreased amount, abnormal foxc1aua1017/ua1017; foxc1bua1018/ua1018 standard conditions Fig. 8 with image from Whitesell et al., 2019
vascular associated smooth muscle cell acta2 expression decreased amount, abnormal foxc1aua1017/ua1017; foxc1bua1018/ua1018 standard conditions Fig. 8 with image from Whitesell et al., 2019
pericyte pdgfrb expression decreased amount, abnormal foxc1aua1017/ua1017; foxc1bua1018/ua1018 standard conditions Fig. 8 with image from Whitesell et al., 2019
determination of heart left/right asymmetry disrupted, abnormal foxc1aua1017/ua1017; foxc1bua1018/ua1018 (AB) standard conditions Figure 3 with image from Chrystal et al., 2021
brain hemorrhagic, abnormal foxc1aua1017/ua1017; foxc1bua1018/ua1018 (AB) standard conditions Figure 2 with image from Chrystal et al., 2021
pericardium edematous, abnormal foxc1aua1017/ua1017; foxc1bua1018/ua1018 (AB) standard conditions Figure 4 with image from Hawkey-Noble et al., 2022
Figure 2 with image from Chrystal et al., 2021
opercular flap ossification decreased process quality, abnormal foxc1aua1017/ua1017; foxc1bua1018/ua1018 (AB) standard conditions Figure 4 with image from Hawkey-Noble et al., 2022
heart myl7 expression spatial pattern, abnormal foxc1aua1017/ua1017; foxc1bua1018/ua1018 (AB) standard conditions Figure 3 with image from Chrystal et al., 2021
determination of liver left/right asymmetry disrupted, abnormal foxc1aua1017/ua1017; foxc1bua1018/ua1018 (AB) standard conditions Figure 3 with image from Chrystal et al., 2021
lateral plate mesoderm lft2 expression spatial pattern, abnormal foxc1aua1017/ua1017; foxc1bua1018/ua1018 (AB) standard conditions Figure 6 with image from Chrystal et al., 2021
brain ventricular system swollen, abnormal foxc1aua1017/ua1017; foxc1bua1018/ua1018 (AB) standard conditions Figure 2 with image from Chrystal et al., 2021
pancreas foxa3 expression spatial pattern, abnormal foxc1aua1017/ua1017; foxc1bua1018/ua1018 (AB) standard conditions Figure 3 with image from Chrystal et al., 2021
pharyngeal arch 1 ossification decreased process quality, abnormal foxc1aua1017/ua1017; foxc1bua1018/ua1018 (AB) standard conditions Figure 4 with image from Hawkey-Noble et al., 2022
eye decreased size, abnormal foxc1aua1017/ua1017; foxc1bua1018/ua1018 (AB) standard conditions Figure 2 with image from Chrystal et al., 2021
pharyngeal arch 2 ossification decreased process quality, abnormal foxc1aua1017/ua1017; foxc1bua1018/ua1018 (AB) standard conditions Figure 4 with image from Hawkey-Noble et al., 2022
head deformed, abnormal foxc1aua1017/ua1017; foxc1bua1018/ua1018 (AB) standard conditions Figure 2 with image from Chrystal et al., 2021
liver foxa3 expression spatial pattern, abnormal foxc1aua1017/ua1017; foxc1bua1018/ua1018 (AB) standard conditions Figure 3 with image from Chrystal et al., 2021
determination of pancreatic left/right asymmetry disrupted, abnormal foxc1aua1017/ua1017; foxc1bua1018/ua1018 (AB) standard conditions Figure 3 with image from Chrystal et al., 2021
ventral aorta vascular associated smooth muscle cell decreased amount, abnormal foxc1aua1017/ua1017; foxc1bua1018/ua1018; ca7Tg/+; ci5Tg/+ standard conditions Fig. 8 with image from Whitesell et al., 2019
cranial cartilage ossification absent process, abnormal foxc1bua1018/ua1018; foxl1nfl1/nfl1 (AB) standard conditions Figure 6 with image from Hawkey-Noble et al., 2022
vertebra ossification absent process, abnormal foxc1bua1018/ua1018; foxl1nfl1/nfl1 (AB) standard conditions Figure 6 with image from Hawkey-Noble et al., 2022
coelom edematous, abnormal foxc1bua1018/ua1018; foxl1nfl1/nfl1 (AB) standard conditions Figure 6 with image from Hawkey-Noble et al., 2022
Citations