CRISPR

CRISPR1-atrx

ID

ZDB-CRISPR-191004-1

Name

CRISPR1-atrx

Previous Names

None

Target

atrx (1)

Sequence

5' - GGTCCTGAGTTCCGTAACAA - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
zdf36	atrx
zdf37	atrx
zdf38	atrx

Expression

Gene expression in Wild Types + CRISPR1-atrx

No data available

Phenotype

Phenotype resulting from CRISPR1-atrx

No data available

Phenotype of all Fish created by or utilizing CRISPR1-atrx

Phenotype	Fish	Conditions	Figures
whole organism decreased life span, abnormal	atrx^zdf36/zdf36 (AB)	standard conditions	Fig 1 from Oppel et al., 2019
whole organism dead, abnormal	atrx^zdf36/zdf36 (AB)	standard conditions	Fig 1 from Oppel et al., 2019
caudal hematopoietic tissue hbae1.1 expression decreased amount, abnormal	atrx^zdf36/zdf36 (AB)	standard conditions	Fig 2 from Oppel et al., 2019
whole organism curved, abnormal	atrx^zdf36/zdf36 (AB)	standard conditions	Fig 1 from Oppel et al., 2019
caudal hematopoietic tissue GFP expression increased amount, abnormal	atrx^zdf36/zdf36; la781Tg	standard conditions	Fig 2 from Oppel et al., 2019
head kidney GFP expression increased amount, abnormal	atrx^zdf36/zdf36; la781Tg	standard conditions	Fig 2 from Oppel et al., 2019
erythroid lineage cell increased accumulation heart, abnormal	atrx^zdf36/zdf36; la781Tg	standard conditions	Fig 2 from Oppel et al., 2019
erythroid lineage cell increased accumulation caudal hematopoietic tissue, abnormal	atrx^zdf36/zdf36; la781Tg	standard conditions	Fig 2 from Oppel et al., 2019
heart GFP expression increased amount, abnormal	atrx^zdf36/zdf36; la781Tg	standard conditions	Fig 2 from Oppel et al., 2019
erythroid lineage cell increased accumulation head kidney, abnormal	atrx^zdf36/zdf36; la781Tg	standard conditions	Fig 2 from Oppel et al., 2019
nucleate erythrocyte shape, abnormal	atrx^zdf36/zdf36; la781Tg	standard conditions	Fig 2 from Oppel et al., 2019
whole organism neoplastic, abnormal	tp53^zdf1/zdf1; atrx^zdf37/+; nf1b^p303/p303	standard conditions	Fig 3 , Fig 4 from Oppel et al., 2019
whole organism neoplasm increased amount, abnormal	tp53^zdf1/zdf1; atrx^zdf37/+; nf1b^p303/p303	standard conditions	Fig 3 , Fig 4 from Oppel et al., 2019
whole organism neoplastic, abnormal	tp53^zdf1/zdf1; atrx^zdf37/+; nf1a^p301/+; nf1b^p303/p303	standard conditions	Fig 3 , Fig 4 from Oppel et al., 2019
whole organism neoplasm increased amount, abnormal	tp53^zdf1/zdf1; atrx^zdf37/+; nf1a^p301/+; nf1b^p303/p303	standard conditions	Fig 3 , Fig 4 from Oppel et al., 2019

Citations