FIGURE SUMMARY
Title

Paeonolum protects against MPP(+)-induced neurotoxicity in zebrafish and PC12 cells

Authors
Lu, X.L., Lin, Y.H., Wu, Q., Su, F.J., Ye, C.H., Shi, L., He, B.X., Huang, F.W., Pei, Z., Yao, X.L.
Source
Full text @ BMC Complement Altern Med
Fig. 1

Paeonolum attenuated the MPP+-induced neurotoxicity in zebrafish. (A) Representative brightfield images of zebrafish larvae at 5 dpf. Treatment with MPP+ or paeonolum for up to 5 dpf did not adversely affect the normal development of zebrafish larvae. (B) Paeonolum attenuated MPP+-induced DA neurotoxicity in zebrafish larvae.

Fig. 2

Paeonolum attenuated the MPP+-induced decrease in the locomotor activity of larval zebrafish. (A) The locomotor activity was measured as the speed of control fish and fish exposed to 100 and 1000 µM of MPP+ (n = 4 groups of 15 larvae per group). (B) Locomotor activity of control, MPP+ and paeonolum-treated zebrafish larvae (n = 4 × 15). Error bars represent S.E.M. *P < 0.01.
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ BMC Complement Altern Med
Your Input Welcome
We welcome your input and comments. Please use this form to recommend updates to the information in ZFIN. We appreciate as much detail as possible and references as appropriate. We will review your comments promptly.
Please check the highlighted fields and try again.
Thank you for submitting comments. Your input has been emailed to ZFIN curators who may contact you if additional information is required.
Oops. Something went wrong. Please try again later.