Publication	Data		Fish	Anatomy
Guner-Ataman et al., 2018	Fig. 5		gdf3fb20a/fb20a	cephalic mesoderm absent, abnormal trunk mesoderm absent, abnormal whole organism morphology, abnormal
	Fig. S6		gdf3fb20a/fb20a	adductor mandibulae absent, abnormal adductor operculi absent, abnormal anterior lateral plate mesoderm nkx2.5 expression absent, abnormal bulbus arteriosus absent, abnormal dilatator operculi absent, abnormal hyohyoideus absent, abnormal interhyoideus absent, abnormal levator arcus palatini absent, abnormal levator operculi absent, abnormal pharyngeal arch 3 tie1 expression absent, abnormal pharyngeal arch 3 absent, abnormal pharyngeal arch 4 tie1 expression absent, abnormal pharyngeal arch 4 absent, abnormal pharyngeal arch 5 tie1 expression absent, abnormal pharyngeal arch 5 absent, abnormal ventral intermandibularis anterior absent, abnormal ventral intermandibularis posterior absent, abnormal
	Fig. S7		gdf3fb20a/fb20a	whole organism morphology, abnormal
Bisgrove et al., 2017	Fig. 1		gdf3zy51/zy51 (AB) ,   gdf3zy52/zy52 (AB)	brain ventro-medial region foxa2 expression absent, abnormal central nervous system anterior region malformed, abnormal eye fused with eye, abnormal floor plate spinal cord region foxa2 expression absent, abnormal heart tube hand2 expression absent, abnormal notochord tbxta expression absent, abnormal notochord absent, abnormal pectoral fin bud hand2 expression absent, abnormal pharyngeal endoderm foxa2 expression absent, abnormal pharyngeal endoderm absent, abnormal pharyngeal mesoderm hand2 expression absent, abnormal somite myod1 expression spatial pattern, abnormal somite decreased size, abnormal somite U-shaped, abnormal spinal cord neuron tbx16 expression absent, abnormal
	Fig. 2		gdf3zy51/zy51 (AB) ,   gdf3zy52/zy52 (AB)	anterior neural plate otx2b expression decreased distribution, abnormal axial chorda mesoderm lft1 expression absent, abnormal axial chorda mesoderm tbxta expression absent, abnormal axial hypoblast foxa2 expression absent, abnormal axial mesoderm anterior region ndr2 expression absent, abnormal axial mesoderm posterior region ndr2 expression absent, abnormal endoderm foxa2 expression absent, abnormal endoderm sox17 expression decreased amount, abnormal forerunner cell group sox17 expression decreased amount, abnormal hypoblast lft1 expression absent, abnormal hypoblast tbx16 expression absent, abnormal margin ventral region eve1 expression decreased distribution, abnormal neuroectoderm gsc expression absent, abnormal neuroectoderm lft1 expression absent, abnormal neuroectoderm lft2 expression absent, abnormal neuroectoderm ndr2 expression absent, abnormal prechordal plate gsc expression absent, abnormal prechordal plate lft1 expression absent, abnormal prechordal plate lft2 expression absent, abnormal prechordal plate tbx16 expression decreased distribution, abnormal
	Fig. 3		gdf3zy51/zy51 (AB) ,   gdf3zy52/zy52 (AB)	central nervous system anterior region malformed, abnormal germ ring gsc expression absent, abnormal germ ring tbxta expression spatial pattern, abnormal germ ring dorsal region tbxta expression decreased amount, abnormal notochord absent, abnormal whole organism morphology, abnormal
Montague et al., 2017	Fig. 1		gdf3a165/+ (AB/TL) ,   gdf3a164/+ (AB/TL)	mesendoderm development decreased process quality, abnormal
	Fig. 1-S2		gdf3a165/a165 (AB/TL) ,   gdf3a164/a164 (AB/TL)	heart position, abnormal lateral plate mesoderm spaw expression mislocalised, abnormal
	Fig. 2		gdf3a165/a165 (AB/TL) ,   gdf3a165/+ (AB/TL) ,   gdf3a164/+ (AB/TL) ,   gdf3a164/a164 (AB/TL)	embryonic structure ndr1 expression decreased amount, abnormal embryonic structure ndr2 expression decreased amount, abnormal hypoblast sox32 expression decreased amount, abnormal margin gsc expression absent, abnormal margin lft1 expression absent, abnormal margin ndr1 expression decreased amount, abnormal margin ndr2 expression decreased amount, abnormal margin tbxta expression decreased amount, abnormal mesendoderm development decreased process quality, abnormal whole organism lft1 expression decreased amount, abnormal
Pelliccia et al., 2017	Fig. 1		gdf3pr05 ,   gdf3pr05/pr05	endoderm formation decreased occurrence, abnormal mesoderm formation decreased occurrence, abnormal whole organism morphology, abnormal
	Fig. 2		gdf3pr05/+ ,   gdf3pr05/pr05	margin lft1 expression absent, abnormal margin ndr2 expression absent, abnormal margin sox17 expression absent, abnormal margin dorsal region tbxta expression absent, abnormal whole organism dorsal region foxa2 expression absent, abnormal whole organism dorsal region gsc expression absent, abnormal whole organism dorsal region noto expression absent, abnormal
	Fig. 3		gdf3pr05/pr05	whole organism dorsal region chrd expression decreased amount, abnormal whole organism dorsal region chrd expression decreased distribution, abnormal whole organism dorsal region gsc expression absent, abnormal whole organism ventral region eve1 expression increased amount, abnormal whole organism ventral region eve1 expression increased distribution, abnormal whole organism ventral region ab1-smad labeling increased amount, abnormal whole organism ventral region ab1-smad labeling increased distribution, abnormal
	Fig. 4		WT + MO2-gdf3 ,   s870Tg + MO2-gdf3	Kupffer's vesicle dand5 expression spatial pattern, abnormal Kupffer's vesicle cell morphology, abnormal Kupffer's vesicle left side dand5 expression mislocalised, abnormal lateral plate mesoderm spaw expression absent, abnormal left/right pattern formation decreased occurrence, abnormal
Du et al., 2014	Fig. 4		WT + MO2-gdf3 ,   WT + MO5-gdf3	convergent extension involved in gastrulation decreased occurrence, abnormal hindbrain neural keel increased width, abnormal neural plate increased width, abnormal notochord curved, abnormal notochord decreased length, abnormal prechordal plate mislocalised posteriorly, abnormal rhombomere increased width, abnormal somite antero-posteriorly flattened, abnormal somite distended, abnormal
	Fig. 5		WT + MO2-gdf3 ,   WT + MO5-gdf3	convergent extension involved in gastrulation decreased occurrence, abnormal
Peterson et al., 2013	Fig. 1		WT + MO3-gdf3 ,   WT + MO4-gdf3	determination of heart left/right asymmetry decreased process quality, abnormal determination of left/right asymmetry in diencephalon decreased process quality, abnormal diencephalon bilateral symmetry, abnormal heart bilateral symmetry, abnormal heart looping decreased process quality, abnormal heart tube bilateral symmetry, abnormal lateral plate mesoderm determination of left/right asymmetry in lateral mesoderm decreased process quality, abnormal
	Fig. 4		WT + MO3-gdf3	Kupffer's vesicle motile cilium decreased length, abnormal
Li et al., 2012	Fig. 2		AB + MO2-gdf3	heart development disrupted, abnormal pericardium edematous, abnormal trunk curved, abnormal
	Fig. 3		f1Tg + MO2-gdf3	cardiac ventricle decreased size, abnormal heart looping disrupted, abnormal heart tubular, abnormal pericardium edematous, abnormal
	Fig. 4		AB + MO2-gdf3	brain neuron decreased branchiness, abnormal post-vent region neuron development disrupted, abnormal trunk neuron development disrupted, abnormal
Ye et al., 2010	Fig. 4		AB + MO1-gdf3 ,   AB + MO2-gdf3	eye decreased size, abnormal eye perforate, abnormal lens decreased size, abnormal optic fissure closure incomplete, abnormal post-vent region curved ventral, abnormal post-vent region decreased length, abnormal retina decreased size, abnormal skeletal system morphology, abnormal
	Fig. 5		AB + MO1-gdf3	eye decreased size, abnormal retina photoreceptor outer segment absent, abnormal retina photoreceptor outer segment decreased length, abnormal