PUBLICATION
Restoration of anatomical continuity after spinal cord transection depends on Wnt/β-catenin signaling in larval zebrafish
- Authors
- Wehner, D., Becker, T., Becker, C.G.
- ID
- ZDB-PUB-171206-9
- Date
- 2017
- Source
- Data in brief 16: 65-70 (Journal)
- Registered Authors
- Becker, Catherina G., Becker, Thomas, Wehner, Daniel
- Keywords
- Beta-catenin, Regeneration, Spinal cord, Wnt, Zebrafish
- MeSH Terms
- none
- PubMed
- 29204466 Full text @ Data Brief
Citation
Wehner, D., Becker, T., Becker, C.G. (2017) Restoration of anatomical continuity after spinal cord transection depends on Wnt/β-catenin signaling in larval zebrafish. Data in brief. 16:65-70.
Abstract
This data article contains descriptive and experimental data on spinal cord regeneration in larval zebrafish and its dependence on Wnt/β-catenin signaling. Analyzing spread of intraspinally injected fluorescent dextran showed that anatomical continuity is rapidly restored after complete spinal cord transection. Pharmacological interference with Wnt/β-catenin signaling (IWR-1) impaired restoration of spinal continuity. For further details and experimental findings please refer to the research article by Wehner et al. Wnt signaling controls pro-regenerative Collagen XII in functional spinal cord regeneration in zebrafish (Wehner et al., 2017) [1].
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping