ZFIN Morpholino: MO5-foxj1a

Target Location

Genome Build: GRCz11Chromosome: 3

Genomic Features

No data available

Expression

Gene expression in Wild Types + MO5-foxj1a

No data available

Phenotype

Phenotype resulting from MO5-foxj1a

No data available

Phenotype of all Fish created by or utilizing MO5-foxj1a

Phenotype	Fish	Conditions	Figures
renal tubule development process quality, abnormal	WT + MO5-foxj1a + MO6-foxj1a	physical alteration: anatomical structure	Fig. 4 from Hellman et al., 2010
central canal motile cilium immobile, abnormal	WT + MO5-foxj1a + MO6-foxj1a	standard conditions	Fig. 3 from Hellman et al., 2010
epithelial cilium movement involved in extracellular fluid movement arrested, abnormal	WT + MO5-foxj1a + MO6-foxj1a	standard conditions	Fig. 3 from Hellman et al., 2010
response to wounding decreased process quality, abnormal	WT + MO5-foxj1a + MO6-foxj1a	standard conditions	Fig. 4 from Hellman et al., 2010
Kupffer's vesicle motile cilium immobile, abnormal	WT + MO5-foxj1a + MO6-foxj1a	standard conditions	Fig. 3 from Hellman et al., 2010

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Citations

Include unpublished citations

Austin-Tse, C., Halbritter, J., Zariwala, M.A., Gilberti, R.M., Gee, H.Y., Hellman, N., Pathak, N., Liu, Y., Panizzi, J.R., Patel-King, R.S., Tritschler, D., Bower, R., O'Toole, E., Porath, J.D., Hurd, T.W., Chaki, M., Diaz, K.A., Kohl, S., Lovric, S., Hwang, D.Y., Braun, D.A., Schueler, M., Airik, R., Otto, E.A., Leigh, M.W., Noone, P.G., Carson, J.L., Davis, S.D., Pittman, J.E., Ferkol, T.W., Atkinson, J.J., Olivier, K.N., Sagel, S.D., Dell, S.D., Rosenfeld, M., Milla, C.E., Loges, N.T., Omran, H., Porter, M.E., King, S.M., Knowles, M.R., Drummond, I.A., and Hildebrandt, F. (2013) Zebrafish Ciliopathy Screen Plus Human Mutational Analysis Identifies C21orf59 and CCDC65 Defects as Causing Primary Ciliary Dyskinesia. American journal of human genetics. 93(4):672-686
Panizzi, J.R., Becker-Heck, A., Castleman, V.H., Al-Mutairi, D.A., Liu, Y., Loges, N.T., Pathak, N., Austin-Tse, C., Sheridan, E., Schmidts, M., Olbrich, H., Werner, C., Häffner, K., Hellman, N., Chodhari, R., Gupta, A., Kramer-Zucker, A., Olale, F., Burdine, R.D., Schier, A.F., O'Callaghan, C., Chung, E.M., Reinhardt, R., Mitchison, H.M., King, S.M., Omran, H., and Drummond, I.A. (2012) CCDC103 mutations cause primary ciliary dyskinesia by disrupting assembly of ciliary dynein arms. Nature Genetics. 44(6):714-719
Hellman, N.E., Liu, Y., Merkel, E., Austin, C., Le Corre, S., Beier, D.R., Sun, Z., Sharma, N., Yoder, B.K., and Drummond, I.A. (2010) The zebrafish foxj1a transcription factor regulates cilia function in response to injury and epithelial stretch. Proceedings of the National Academy of Sciences of the United States of America. 107(43):18499-18504

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