Morpholino

MO1-prickle1b

ID
ZDB-MRPHLNO-071221-3
Name
MO1-prickle1b
Previous Names
  • Pk1b-MO-SA-I3E4 (1)
Target
Sequence
5' - GGCAGTAGCGAATCTGTGTTGAAGC - 3'
ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Disclaimer
Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.
Note
Splice blocking morpholino against the intron3-exon4 boundary.
Genome Resources
None
Target Location
Genomic Features
No data available
Expression
Gene expression in Wild Types + MO1-prickle1b
Expressed Gene Anatomy Figures
cdh1 Fig. 9 with image from Ahsan et al., 2019
Phenotype
Phenotype resulting from MO1-prickle1b
Phenotype Fish Figures
migratory cranial neural crest establishment of cell polarity disrupted, abnormal vu234Tg + MO1-prickle1b Fig. 6 with image from Ahsan et al., 2019
migratory neural crest lobed, abnormal WT + MO1-prickle1b Fig. 8 with image from Ahsan et al., 2019
migratory neural crest ovate, abnormal vu234Tg + MO1-prickle1b Fig. 2 with image from Ahsan et al., 2019
migratory neural crest positional polarity, abnormal vu234Tg + MO1-prickle1b Fig. 6 with image from Ahsan et al., 2019
migratory neural crest cell ab6-cdh2 labeling decreased amount, abnormal WT + MO1-prickle1b Fig. 9 with image from Ahsan et al., 2019
migratory neural crest cell cdh1 expression increased amount, abnormal WT + MO1-prickle1b Fig. 9 with image from Ahsan et al., 2019
migratory neural crest cell bleb increased amount, abnormal WT + MO1-prickle1b Fig. 8 with image from Ahsan et al., 2019
migratory neural crest cell filopodium absent, abnormal WT + MO1-prickle1b Fig. 8 with image from Ahsan et al., 2019
migratory neural crest cell lamellipodium absent, abnormal WT + MO1-prickle1b Fig. 8 with image from Ahsan et al., 2019
premigratory neural crest cell cdh1 expression increased amount, abnormal WT + MO1-prickle1b Fig. 9 with image from Ahsan et al., 2019
whole organism anterior-posterior axis decreased length, abnormal vu234Tg + MO1-prickle1b Fig. 2 with image from Ahsan et al., 2019
whole organism medial-lateral axis increased length, abnormal vu234Tg + MO1-prickle1b Fig. 2 with image from Ahsan et al., 2019
Phenotype of all Fish created by or utilizing MO1-prickle1b
Phenotype Fish Conditions Figures
migratory neural crest lobed, abnormal WT + MO1-prickle1b standard conditions Fig. 8 with image from Ahsan et al., 2019
migratory neural crest cell ab6-cdh2 labeling decreased amount, abnormal WT + MO1-prickle1b standard conditions Fig. 9 with image from Ahsan et al., 2019
migratory neural crest cell bleb increased amount, abnormal WT + MO1-prickle1b standard conditions Fig. 8 with image from Ahsan et al., 2019
migratory neural crest cell lamellipodium absent, abnormal WT + MO1-prickle1b standard conditions Fig. 8 with image from Ahsan et al., 2019
premigratory neural crest cell cdh1 expression increased amount, abnormal WT + MO1-prickle1b standard conditions Fig. 9 with image from Ahsan et al., 2019
migratory neural crest cell filopodium absent, abnormal WT + MO1-prickle1b standard conditions Fig. 8 with image from Ahsan et al., 2019
migratory neural crest cell cdh1 expression increased amount, abnormal WT + MO1-prickle1b standard conditions Fig. 9 with image from Ahsan et al., 2019
facial nerve motor nucleus mislocalised anteriorly, abnormal WT + MO1-prickle1b + MO2-prickle1b standard conditions Fig. S3 with image from Mapp et al., 2011
rhombomere 4 development disrupted, abnormal WT + MO1-prickle1b + MO2-prickle1b standard conditions Fig. 6 with image from Rohrschneider et al., 2007
facial nerve motor nucleus motor neuron mislocalised, abnormal WT + MO1-prickle1b + MO2-prickle1b standard conditions Fig. 6 with image from Rohrschneider et al., 2007
neuron migration process quality, abnormal WT + MO1-prickle1b + MO2-prickle1b standard conditions Fig. S3 with image from Mapp et al., 2011
hindbrain tangential cell migration disrupted, abnormal WT + MO1-prickle1b + MO2-prickle1b standard conditions Fig. 6 with image from Rohrschneider et al., 2007
convergent extension involved in axis elongation process quality, abnormal WT + MO1-prickle1b + MO2-prickle1b control Fig. S1 with image from Mapp et al., 2010
neuron migration process quality, abnormal ch100Tg + MO1-prickle1b + MO2-prickle1b standard conditions Fig. 4 with image from Mapp et al., 2011
facial nerve motor nucleus nucleus physical object quality, abnormal ch100Tg + MO1-prickle1b + MO2-prickle1b standard conditions Fig. 6 with image,  Fig. S6 with image from Mapp et al., 2011
protein localization to nucleus process quality, abnormal ch100Tg + MO1-prickle1b + MO2-prickle1b standard conditions Fig. 6 with image,  Fig. S6 with image from Mapp et al., 2011
facial nerve motor nucleus mislocalised anteriorly, abnormal ch100Tg + MO1-prickle1b + MO2-prickle1b standard conditions Fig. 4 with image from Mapp et al., 2011
branchiomotor neuron rhombomere 6 absent, abnormal ch100Tg + MO1-prickle1b + MO2-prickle1b (AB) control Fig. 4 with image,  Fig. 5,  Fig. 6 with image from Mapp et al., 2010
branchiomotor neuron neuron projection amount, abnormal ch100Tg + MO1-prickle1b + MO2-prickle1b (AB) control Fig. 3 from Mapp et al., 2010
branchiomotor neuron accumulation rhombomere 4, abnormal ch100Tg + MO1-prickle1b + MO2-prickle1b (AB) control Fig. 2 with image,  Fig. 3,  Fig. 4 with image,  Fig. 5,  Fig. 6 with image from Mapp et al., 2010
branchiomotor neuron motor neuron migration process quality, abnormal ch100Tg + MO1-prickle1b + MO2-prickle1b (AB) control Fig. 2 with image,  Fig. 3,  Fig. 4 with image from Mapp et al., 2010
branchiomotor neuron centrosome position, abnormal ch100Tg + MO1-prickle1b + MO2-prickle1b (AB) control Fig. 6 with image from Mapp et al., 2010
branchiomotor neuron decreased speed, abnormal ch100Tg + MO1-prickle1b + MO2-prickle1b (AB) control Fig. 2 with image from Mapp et al., 2010
branchiomotor neuron neuron projection orientation rhombomere 4, abnormal ch100Tg + MO1-prickle1b + MO2-prickle1b (AB) control Fig. 3 from Mapp et al., 2010
branchiomotor neuron cell body orientation branchiomotor neuron axon, abnormal ch100Tg + MO1-prickle1b + MO2-prickle1b (AB) control Fig. 4 with image,  Fig. 5 from Mapp et al., 2010
branchiomotor neuron cell body shape, abnormal ch100Tg + MO1-prickle1b + MO2-prickle1b (AB) control Fig. 4 with image from Mapp et al., 2010
branchiomotor neuron rhombomere 5 absent, abnormal ch100Tg + MO1-prickle1b + MO2-prickle1b (AB) control Fig. 4 with image,  Fig. 5,  Fig. 6 with image from Mapp et al., 2010
branchiomotor neuron neuron projection length, abnormal ch100Tg + MO1-prickle1b + MO2-prickle1b (AB) control Fig. 3 from Mapp et al., 2010
neuron migration process quality, abnormal rw0Tg + MO1-prickle1b + MO2-prickle1b standard conditions Fig. 2 with image from Mapp et al., 2011
facial nerve motor nucleus mislocalised anteriorly, abnormal rw0Tg + MO1-prickle1b + MO2-prickle1b standard conditions Fig. 2 with image from Mapp et al., 2011
migratory cranial neural crest establishment of cell polarity disrupted, abnormal vu234Tg + MO1-prickle1b standard conditions Fig. 6 with image from Ahsan et al., 2019
migratory neural crest positional polarity, abnormal vu234Tg + MO1-prickle1b standard conditions Fig. 6 with image from Ahsan et al., 2019
migratory neural crest ovate, abnormal vu234Tg + MO1-prickle1b standard conditions Fig. 2 with image from Ahsan et al., 2019
whole organism anterior-posterior axis decreased length, abnormal vu234Tg + MO1-prickle1b standard conditions Fig. 2 with image from Ahsan et al., 2019
whole organism medial-lateral axis increased length, abnormal vu234Tg + MO1-prickle1b standard conditions Fig. 2 with image from Ahsan et al., 2019
facial nerve motor nucleus mislocalised anteriorly, abnormal hmgcrbs617/+; rw0Tg + MO1-prickle1b + MO2-prickle1b standard conditions Fig. S3 with image from Mapp et al., 2011
neuron migration process quality, abnormal hmgcrbs617/+; rw0Tg + MO1-prickle1b + MO2-prickle1b standard conditions Fig. S3 with image from Mapp et al., 2011
facial nerve motor nucleus mislocalised anteriorly, abnormal hmgcrbs617/s617; rw0Tg + MO1-prickle1b + MO2-prickle1b standard conditions Fig. S3 with image from Mapp et al., 2011
neuron migration process quality, abnormal hmgcrbs617/s617; rw0Tg + MO1-prickle1b + MO2-prickle1b standard conditions Fig. S3 with image from Mapp et al., 2011
migratory neural crest ovate, abnormal prickle1ach105/ch105; vu234Tg + MO1-prickle1b standard conditions Fig. 2 with image from Ahsan et al., 2019
migratory neural crest patchy, exacerbated prickle1ach105/ch105; vu234Tg + MO1-prickle1b standard conditions Fig. 2 with image from Ahsan et al., 2019
migratory neural crest mislocalised, exacerbated prickle1ach105/ch105; vu234Tg + MO1-prickle1b standard conditions Fig. 2 with image from Ahsan et al., 2019
Citations
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