ZFIN Morpholino: MO1-prkci

Target Location

Genome Build: GRCz11Chromosome: 2

Genomic Features

No data available

Expression

Gene expression in Wild Types + MO1-prkci

No data available

Phenotype

Phenotype resulting from MO1-prkci

Phenotype	Fish	Figures
amacrine cell spatial pattern, abnormal	knu3Tg + MO1-prkci	Fig. 3 from Cui et al., 2007
camera-type eye photoreceptor cell differentiation decreased occurrence, abnormal	AB/EKW + MO1-prkci	Fig. 9 from Krock et al., 2014
dorsal motor nucleus of vagus nerve development disrupted, abnormal	WT + MO1-prkci	Fig. 3 from Ohata et al., 2011
dorsolateral motor nucleus of vagal nerve malformed, abnormal	WT + MO1-prkci	Fig. 3 from Ohata et al., 2011
eye photoreceptor cell apical region decreased length, abnormal	AB/EKW + MO1-prkci	Fig. 8 from Krock et al., 2014

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Phenotype of all Fish created by or utilizing MO1-prkci

Phenotype	Fish	Conditions	Figures
eye photoreceptor cell apical region decreased length, abnormal	AB/EKW + MO1-prkci	standard conditions	Fig. 8 from Krock et al., 2014
retina has fewer parts of type retinal rod cell, abnormal	AB/EKW + MO1-prkci	standard conditions	Fig. 9 from Krock et al., 2014
photoreceptor cell morphogenesis decreased process quality, abnormal	AB/EKW + MO1-prkci	standard conditions	Fig. 8 from Krock et al., 2014
camera-type eye photoreceptor cell differentiation decreased occurrence, abnormal	AB/EKW + MO1-prkci	standard conditions	Fig. 9 from Krock et al., 2014
peridermal cell actin-based cell projection decreased length, abnormal	TU + MO1-prkci	standard conditions	Fig. 1 from Raman et al., 2016

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Citations

Include unpublished citations

Raman, R., Damle, I., Rote, R., Banerjee, S., Dingare, C., Sonawane, M. (2016) aPKC regulates apical localization of Lgl to restrict elongation of microridges in developing zebrafish epidermis. Nature communications. 7:11643
Strzyz, P.J., Lee, H.O., Sidhaye, J., Weber, I.P., Leung, L.C., Norden, C. (2015) Interkinetic Nuclear Migration Is Centrosome Independent and Ensures Apical Cell Division to Maintain Tissue Integrity. Developmental Cell. 32(2):203-19
Gerlach, G.F., Wingert, R.A. (2014) Zebrafish pronephros tubulogenesis and epithelial identity maintenance are reliant on the polarity proteins Prkc iota and zeta. Developmental Biology. 396(2):183-200
Krock, B.L., Perkins, B.D. (2014) The Par-PrkC Polarity Complex Is Required for Cilia Growth in Zebrafish Photoreceptors. PLoS One. 9:e104661
Cibrián Uhalte, E., Kirchner, M., Hellwig, N., Allen, J.J., Donat, S., Shokat, K.M., Selbach, M., and Abdelilah-Seyfried, S. (2012) In vivo conditions to identify prkci phosphorylation targets using the analog-sensitive kinase method in zebrafish. PLoS One. 7(6):e40000
Ohata, S., Aoki, R., Kinoshita, S., Yamaguchi, M., Tsuruoka-Kinoshita, S., Tanaka, H., Wada, H., Watabe, S., Tsuboi, T., Masai, I., and Okamoto, H. (2011) Dual Roles of Notch in Regulation of Apically Restricted Mitosis and Apicobasal Polarity of Neuroepithelial Cells. Neuron. 69(2):215-230
Alexandre, P., Reugels, A.M., Barker, D., Blanc, E., and Clarke, J.D. (2010) Neurons derive from the more apical daughter in asymmetric divisions in the zebrafish neural tube. Nature Neuroscience. 13(6):673-679
Garavito-Aguilar, Z.V., Riley, H.E., and Yelon, D. (2010) Hand2 ensures an appropriate environment for cardiac fusion by limiting Fibronectin function. Development (Cambridge, England). 137(19):3215-3220
Grant, P.K., and Moens, C.B. (2010) The neuroepithelial basement membrane serves as a boundary and a substrate for neuron migration in the zebrafish hindbrain. Neural Development. 5:9
Hava, D., Forster, U., Matsuda, M., Cui, S., Link, B.A., Eichhorst, J., Wiesner, B., Chitnis, A., and Abdelilah-Seyfried, S. (2009) Apical membrane maturation and cellular rosette formation during morphogenesis of the zebrafish lateral line. Journal of Cell Science. 122(Pt 5):687-695

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