ZFIN Morpholino: MO4-neurog1

Target Location

Genome Build: GRCz11Chromosome: 14

Genomic Features

No data available

Expression

Gene expression in Wild Types + MO4-neurog1

No data available

Phenotype

Phenotype resulting from MO4-neurog1

Phenotype	Fish	Figures
neuromast mislocalised, abnormal	sqet20Et + MO4-neurog1	Fig. 8 from Hernandez et al., 2007
otic vesicle neuroblast (sensu Vertebrata) physical object quality, abnormal	AB + MO4-neurog1	Fig. 2 from Hans et al., 2013
otic vesicle neuroblast (sensu Vertebrata) poorly differentiated, abnormal	AB + MO4-neurog1	Fig. 2 from Hans et al., 2013
otic vesicle neuron differentiation decreased process quality, abnormal	AB + MO4-neurog1	Fig. 2 from Hans et al., 2013
posterior lateral line ganglion absent, abnormal	zf106Tg + MO4-neurog1	Fig. 3 from Sarrazin et al., 2010

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Phenotype of all Fish created by or utilizing MO4-neurog1

Phenotype	Fish	Conditions	Figures
otic vesicle neuron differentiation decreased process quality, abnormal	AB + MO4-neurog1	standard conditions	Fig. 2 from Hans et al., 2013
otic vesicle neuroblast (sensu Vertebrata) physical object quality, abnormal	AB + MO4-neurog1	standard conditions	Fig. 2 from Hans et al., 2013
otic vesicle neuroblast (sensu Vertebrata) poorly differentiated, abnormal	AB + MO4-neurog1	standard conditions	Fig. 2 from Hans et al., 2013
Rohon-Beard neuron decreased amount, abnormal	WT + MO4-neurog1	standard conditions	Fig. 5 from Dyer et al., 2014
neuromast mislocalised, abnormal	sqet20Et + MO4-neurog1	standard conditions	Fig. 8 from Hernandez et al., 2007

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Citations

Include unpublished citations

Dyer, C., Linker, C., Graham, A., Knight, R. (2014) Specification of sensory neurons occurs through diverse developmental programs functioning in the brain and spinal cord. Developmental Dynamics : an official publication of the American Association of Anatomists. 243(11):1429-39
Hans, S., Irmscher, A., and Brand, M. (2013) Zebrafish Foxi1 provides a neuronal ground state during inner ear induction preceding the Dlx3b/4b-regulated sensory lineage. Development (Cambridge, England). 140(9):1936-1945
Yoshizawa, A., Nakahara, Y., Izawa, T., Ishitani, T., Tsutsumi, M., Kuroiwa, A., Itoh, M., and Kikuchi, Y. (2011) Zebrafish Dmrta2 regulates neurogenesis in the telencephalon. Genes to cells : devoted to molecular & cellular mechanisms. 16(11):1097-1109
Sarrazin, A.F., Nuñez, V.A., Sapède, D., Tassin, V., Dambly-Chaudière, C., and Ghysen, A. (2010) Origin and early development of the posterior lateral line system of zebrafish. The Journal of neuroscience : the official journal of the Society for Neuroscience. 30(24):8234-8244
Scholpp, S., Delogu, A., Gilthorpe, J., Peukert, D., Schindler, S., and Lumsden, A. (2009) Her6 regulates the neurogenetic gradient and neuronal identity in the thalamus. Proceedings of the National Academy of Sciences of the United States of America. 106(47):19895-19900
Hernandez, P.P., Olivari, F.A., Sarrazin, A.F., Sandoval, P.C., and Allende, M.L. (2007) Regeneration in zebrafish lateral line neuromasts: Expression of the neural progenitor cell marker sox2 and proliferation-dependent and-independent mechanisms of hair cell renewal. Developmental Neurobiology. 67(5):637-654
Li, W., and Cornell, R.A. (2007) Redundant activities of Tfap2a and Tfap2c are required for neural crest induction and development of other non-neural ectoderm derivatives in zebrafish embryos. Developmental Biology. 304(1):338-354
Bricaud, O., and Collazo, A. (2006) The transcription factor six1 inhibits neuronal and promotes hair cell fate in the developing zebrafish (Danio rerio) inner ear. The Journal of neuroscience : the official journal of the Society for Neuroscience. 26(41):10438-10451
Sarrazin, A.F., Villablanca, E.J., Nunez, V.A., Sandoval, P.C., Ghysen, A., and Allende, M.L. (2006) Proneural gene requirement for hair cell differentiation in the zebrafish lateral line. Developmental Biology. 295(2):534-545
Bae, Y.K., Shimizu, T., and Hibi, M. (2005) Patterning of proneuronal and inter-proneuronal domains by hairy- and enhancer of split-related genes in zebrafish neuroectoderm. Development (Cambridge, England). 132(6):1375-1385

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