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Fig. 3 Inhibition of MYDGF expression induced neuronal apoptosis-inducing factors in the retina after ONI. Treatment with MYDGF-MO markedly suppressed MYDGF mRNA (a) and Bcl-2 mRNA (b) expression. Under MYDGF inhibition conditions, caspase-3 mRNA (c) and TNFα mRNA (d) expression noticeably increased 1 h and 6 h after ONI. Statistical analysis was performed using one-way ANOVAs, followed by Scheffe’s multiple-comparison tests. Data are expressed as the means ± SEMs (n = 6–7), with statistical significance set at * p < 0.05.
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Full text @ Int. J. Mol. Sci.