Preliminarily unveiling the underlying mechanism of the 30% EF against PD. (A) The PCA of the two datasets. Groups are labeled by different colors (green represents the 6-OHDA group; orange represents the 30% EF group). Microarray platforms are labeled by different shapes (circle represents 6-OHDA group; triangle represents 30% EF group). (B) The volcano plot shows differential protein expressions, comparing 6-OHDA vs. Ctl groups. Blue dots denote down-regulated proteins, red dots indicate up-regulated proteins, and black dots signify proteins with non-significant expression changes. (C) GO biological function analysis. (D) Western blot analysis of 4E-BP1. *** p < 0.001 vs. Ctl; ###p < 0.001 vs. 6-OHDA.
Acknowledgments
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