ZFIN Image: Schmitner et al., 2024, Fig. 8

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Figure Caption

Fig. 8 GKA Dorzagliatin does not induce oxidative stress in β-cells.

agck:GFP and EpRE:RFP expression in the endocrine islet (highlighted in white) of controls and pdx1^-/- treated with DMSO and GKA Dorzagliatin. Scale bar: 20 µm. b β-cells labeled with H2B-RFP in control and pdx1^-/- larvae treated with DMSO and Dorzagliatin. c The absolute β-cell numbers are unchanged upon treatment with Dorzagliatin in controls and pdx1^-/- (N > 3) as shown in a dot plot with indicated mean Statistical significance assessed by One-way ANOVA (<0.0001), P-values of multiple comparisons are indicated.

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Phenotype details

Acknowledgments

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