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FIGURE 2

Observation of the homozygous lethal phenotype and gene expression in bmp7a embryos. (A) Morphological features of the wild-type and bmp7a-/- embryos at 12 hpf, 14 hpf, 17 hpf and after 18 hpf. (B) Morphological features of the wild-type and bmp7a-/- embryos at 16 hpf. The proportion of mutant embryos with different morphology in mutant embryos at 16 hpf was shown in red font. (C) Whole-mount in situ hybridization of the bmp7a gene at 12 hpf, 16 hpf wild-type and bmp7a-/- embryos, and whole-mount in situ hybridization of the bmp7a at 24 hpf wild-type embryos. Scale bars, 200 μm.

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