ZFIN Image: Camiolo et al., 2020, Fig. 1

Image

Figure Caption

Fig. 1

Myeloma cell lines intake and accumulate iron. DMT-1 (A) and FPN-1 (B) mRNA levels in U266, OPM2 and NCI–H929 myeloma cell lines at 6 and 24 h after 400 μM FAC exposure; data are expressed as mean of FC over control; C) LIP evaluated in U266 cells; data are expressed as mean of ΔF ± SEM; ΔF = MFI_CA-AM/DF-MFI_CA-AM. **p-value <0.01 and ***p-value <0.001 versus control. D-F). Cellular ROS production evaluated in U266 (D), OPM2 (E) and NCI–H929 (F) cells after 0.5 and 1 h FAC exposure; data are expressed as mean of dichlorofluorescein (DCF) fluorescence intensity (MFI) ± SEM; G-I) GST (G), SOD2 (H) and HMOX1 (I) mRNA levels in U266 cell line after 0.5 and 24 h treatment with FAC; data are expressed as mean of FC over control. **p-value <0.01 and ***p-value <0.001 versus control.

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Redox Biol.